Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0C1PS
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| Former ID |
DNC008836
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| Drug Name |
9-(3-Hydroxypropyl)-9H-adenine
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| Synonyms |
711-64-8; 9H-Purine-9-propanol, 6-amino-; CHEMBL445974; 9-(3-Hydroxypropyl)-9H-adenine; 3-(6-Amino-9H-purin-9-yl)propan-1-ol; 9-(3-Hydroxypropyl)adenine; Oprea1_108729; 9-(3'-hydroxypropyl)adenine; SCHEMBL1635576; CTK2H3970; DTXSID10500041; MolPort-014-160-140; ZINC5391161; BDBM50257052; 3-(6-aminopurin-9-yl)propan-1-ol; AKOS010941287; 3-(6-Amino-9H-purine-9-yl)-1-propanol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C8H11N5O
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| Canonical SMILES |
C1=NC(=C2C(=N1)N(C=N2)CCCO)N
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| InChI |
1S/C8H11N5O/c9-7-6-8(11-4-10-7)13(5-12-6)2-1-3-14/h4-5,14H,1-3H2,(H2,9,10,11)
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| InChIKey |
BLZBVHFRNUTFCH-UHFFFAOYSA-N
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| CAS Number |
CAS 711-64-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A2a receptor (ADORA2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Rap1 signaling pathway | |||
| Calcium signaling pathway | ||||
| cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Vascular smooth muscle contraction | ||||
| Parkinson's disease | ||||
| Alcoholism | ||||
| Pathwhiz Pathway | Intracellular Signalling Through Adenosine Receptor A2a and Adenosine | |||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | |||
| Reactome | NGF-independant TRKA activation | |||
| Adenosine P1 receptors | ||||
| G alpha (s) signalling events | ||||
| Surfactant metabolism | ||||
| WikiPathways | Nucleotide GPCRs | |||
| Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| NGF signalling via TRKA from the plasma membrane | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A2A and A2B receptors ligands. Bioorg Med Chem. 2009 Apr 1;17(7):2812-22. | |||
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