Drug Information
Drug General Information | Top | |||
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Drug ID |
D0C5LI
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Former ID |
DIB016421
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Drug Name |
SL-91.0893
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Indication | Prostate hyperplasia [ICD-11: GA90; ICD-10: N40] | Terminated | [1] | |
Company |
Synthelabo
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Target and Pathway | Top | |||
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Target(s) | Adrenergic receptor alpha-1D (ADRA1D) | Target Info | Modulator | [2] |
KEGG Pathway | Calcium signaling pathway | |||
cGMP-PKG signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Adrenergic signaling in cardiomyocytes | ||||
Vascular smooth muscle contraction | ||||
Salivary secretion | ||||
NetPath Pathway | IL2 Signaling Pathway | |||
Reactome | Adrenoceptors | |||
G alpha (q) signalling events | ||||
G alpha (12/13) signalling events | ||||
WikiPathways | Monoamine GPCRs | |||
Calcium Regulation in the Cardiac Cell | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007056) | |||
REF 2 | Tissue Selectivity of in vivo alpha1-Adrenoceptor Biding of KMD-3213 in Rats. Eur Urol 1999;36(suppl 1):113-117. |
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