Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0C8ON
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| Former ID |
DNC010369
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| Drug Name |
1-aminoanthracene-9,10-dione
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| Synonyms |
1-AMINOANTHRAQUINONE; 82-45-1; 1-aminoanthracene-9,10-dione; Diazo Fast Red AL; 1-Amino anthraquinone; Anthraquinone, 1-amino-; 1-Aminoanthrachinon; 1-Amino-anthraquinone; 9,10-Anthracenedione, 1-amino-; alpha-Aminoanthraquinone; 1-Amino-9,10-anthraquinone; C.I. 37275; 1-Amino-9,10-anthracenedione; alpha-Anthraquinonylamine; UNII-N5YYY1NEUI; NSC 458; 1-Aminoquinone; .alpha.-Aminoanthraquinone; NSC 30415; 1-Aminoanthrachinon [Czech]; 9,10-Anthracenedione, amino-; N5YYY1NEUI; EINECS 201-423-5; .alpha.-Anthraquinonylamine; BRN 039636
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C14H9NO2
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=CC=C3)N
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| InChI |
1S/C14H9NO2/c15-11-7-3-6-10-12(11)14(17)9-5-2-1-4-8(9)13(10)16/h1-7H,15H2
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| InChIKey |
KHUFHLFHOQVFGB-UHFFFAOYSA-N
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| CAS Number |
CAS 82-45-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A2a receptor (ADORA2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Rap1 signaling pathway | |||
| Calcium signaling pathway | ||||
| cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Vascular smooth muscle contraction | ||||
| Parkinson's disease | ||||
| Alcoholism | ||||
| Pathwhiz Pathway | Intracellular Signalling Through Adenosine Receptor A2a and Adenosine | |||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | |||
| Reactome | NGF-independant TRKA activation | |||
| Adenosine P1 receptors | ||||
| G alpha (s) signalling events | ||||
| Surfactant metabolism | ||||
| WikiPathways | Nucleotide GPCRs | |||
| Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| NGF signalling via TRKA from the plasma membrane | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists. J Med Chem. 2010 Feb 25;53(4):1799-809. | |||
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