Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0D4US
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| Former ID |
DNC013437
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| Drug Name |
4-bromo-1H-indazole
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| Synonyms |
4-bromo-1H-indazole; 186407-74-9; 4-Bromoindazole; 1H-Indazole, 4-bromo-; 4-BROMO (1H)INDAZOLE; 4-Bromo(1H)indazole; CHEMBL246393; 4-bromo-indazole; bromo-1h-indazole; PubChem7834; 4-bromo-2H-indazole; ACMC-1BZDS; 4-bromanyl-1H-indazole; KSC173Q8P; 4-BROMO-7AH-INDAZOLE; SCHEMBL155255; 4-Bromo-1H-indazole, 95%; IND084; AC1Q24I6; Jsp003814; 4-bromo-1h-indazole, 97+%; SCHEMBL16799950; CTK0H3887; HID1021; DTXSID30625169; KJIODOACRIRBPB-UHFFFAOYSA-N; MolPort-022-450-748; MolPort-000-002-423; BCP00013; ACN-S003168; SBB054645; BDBM50209241
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H5BrN2
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| Canonical SMILES |
C1=CC2=C(C=NN2)C(=C1)Br
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| InChI |
1S/C7H5BrN2/c8-6-2-1-3-7-5(6)4-9-10-7/h1-4H,(H,9,10)
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| InChIKey |
KJIODOACRIRBPB-UHFFFAOYSA-N
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| CAS Number |
CAS 186407-74-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nitric-oxide synthase brain (NOS1) | Target Info | Inhibitor | [1] |
| BioCyc | Citrulline-nitric oxide cycle | |||
| KEGG Pathway | Arginine and proline metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Phagosome | ||||
| Circadian entrainment | ||||
| Long-term depression | ||||
| Salivary secretion | ||||
| Alzheimer's disease | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Panther Pathway | CCKR signaling map ST | |||
| Pathwhiz Pathway | Arginine and Proline Metabolism | |||
| Reactome | ROS production in response to bacteria | |||
| Nitric oxide stimulates guanylate cyclase | ||||
| WikiPathways | Monoamine Transport | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
| Spinal Cord Injury | ||||
| Alzheimers Disease | ||||
| Effects of Nitric Oxide | ||||
| Serotonin Transporter Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3177-80. | |||
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