Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0D5ZR
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| Former ID |
DIB009042
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| Drug Name |
TRO-40303
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| Synonyms |
Ischemia-reperfusion injury agent, Trophos; Neuroprotectant (motor neuron disease), Trophos
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| Drug Type |
Small molecular drug
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| Indication | Lateral sclerosis [ICD-11: 8B61] | Discontinued in Phase 2 | [1] | |
| Company |
Trophos SA
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H47NO2
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| Canonical SMILES |
CC(C)CCCC(C)C1CCC2C1(CCC3C2CCC(=NO)C3(C)CCCO)C
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| InChI |
1S/C26H47NO2/c1-18(2)8-6-9-19(3)21-11-12-22-20-10-13-24(27-29)26(5,15-7-17-28)23(20)14-16-25(21,22)4/h18-23,28-29H,6-17H2,1-5H3/b27-24-/t19-,20+,21-,22+,23+,25-,26-/m1/s1
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| InChIKey |
OBKBVSFXEIFOMS-GHCPFUIOSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Translocator protein (TSPO) | Target Info | Modulator | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| HTLV-I infection | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033814) | |||
| REF 2 | Translation of TRO40303 from myocardial infarction models to demonstration of safety and tolerance in a randomized Phase I trial. J Transl Med. 2014; 12: 38. | |||
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