Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0DB9T
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| Former ID |
DNC010554
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| Drug Name |
N-tert-Butyl-1'H-phenothiazine-1'-carboxamide
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| Synonyms |
CHEMBL592431; ChemDiv3_004014; AC1LE08E; Oprea1_837647; MLS001196417; ZINC88008; BRD4081; MolPort-019-755-363; MolPort-002-224-545; HMS2867C08; HMS1484G10; BRD-4081; STK125446; BDBM50308431; AKOS001667641; MCULE-9506670644; CCG-113326; IDI1_021924; N-tert-butylphenothiazine-10-carboxamide; SMR000556301; N-(tert-butyl)phenothiazin-10-ylcarboxamide; ST50857670; EU-0080142; N-tert-butyl-10H-phenothiazine-10-carboxamide; AB00120758-01; N-(tert-butyl)-10H-phenothiazine-10-carboxamide; N-tert-Butyl-1''H-phenothiazine-1''-carboxamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H18N2OS
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| Canonical SMILES |
CC(C)(C)NC(=O)N1C2=CC=CC=C2SC3=CC=CC=C31
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| InChI |
1S/C17H18N2OS/c1-17(2,3)18-16(20)19-12-8-4-6-10-14(12)21-15-11-7-5-9-13(15)19/h4-11H,1-3H3,(H,18,20)
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| InChIKey |
VEHORJYPKNVWKA-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cholinesterase (BCHE) | Target Info | Inhibitor | [1] |
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| WikiPathways | Irinotecan Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants. Bioorg Med Chem. 2010 Mar 15;18(6):2232-2244. | |||
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