Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0DR7A
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| Former ID |
DNC010561
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| Drug Name |
N-p-Tolyl-1'H-phenothiazine-1'-carboxamide
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| Synonyms |
CHEMBL590538; AC1LIMLV; BAS 04087749; Oprea1_350347; MolPort-001-995-161; ZINC527341; STK144993; BDBM50308404; AKOS000643478; MCULE-6324715644; ST50274213; Phenothiazine-10-carboxylic acid p-tolylamide; N-(4-methylphenyl)phenothiazine-10-carboxamide; N-p-Tolyl-1''H-phenothiazine-1''-carboxamide; AB00120046-01; N-(4-methylphenyl)phenothiazin-10-ylcarboxamide; N-(4-methylphenyl)-10H-phenothiazine-10-carboxamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C20H16N2OS
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| Canonical SMILES |
CC1=CC=C(C=C1)NC(=O)N2C3=CC=CC=C3SC4=CC=CC=C42
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| InChI |
1S/C20H16N2OS/c1-14-10-12-15(13-11-14)21-20(23)22-16-6-2-4-8-18(16)24-19-9-5-3-7-17(19)22/h2-13H,1H3,(H,21,23)
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| InChIKey |
AGRMZLFVKVZKOP-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cholinesterase (BCHE) | Target Info | Inhibitor | [1] |
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| WikiPathways | Irinotecan Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants. Bioorg Med Chem. 2010 Mar 15;18(6):2232-2244. | |||
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