Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E0KG
|
|||
| Former ID |
DNC012489
|
|||
| Drug Name |
(R)-3-Methyl-1,2,3,4-tetrahydro-isoquinoline
|
|||
| Synonyms |
(R)-3-Methyl-1,2,3,4-tetrahydroisoquinoline; 179893-97-1; CHEMBL293023; (3R)-3-methyl-1,2,3,4-tetrahydroisoquinoline; AC1OM1IT; (R)-3-Methyl-1,2,3,4-tetrahydro-isoquinoline; SCHEMBL1690519; Isoquinoline, 1,2,3,4-tetrahydro-3-methyl-, (3R)-; UEKQPSAKUNXFHL-MRVPVSSYSA-N; ZINC19928405; FCH952510; BDBM50052885; AKOS024259472; AJ-75700
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C10H13N
|
|||
| Canonical SMILES |
CC1CC2=CC=CC=C2CN1
|
|||
| InChI |
1S/C10H13N/c1-8-6-9-4-2-3-5-10(9)7-11-8/h2-5,8,11H,6-7H2,1H3/t8-/m1/s1
|
|||
| InChIKey |
UEKQPSAKUNXFHL-MRVPVSSYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor alpha-2A (ADRA2A) | Target Info | Inhibitor | [1] |
| Adrenergic receptor alpha-2B (ADRA2B) | Target Info | Inhibitor | [1] | |
| Adrenergic receptor alpha-2C (ADRA2C) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Panther Pathway | Alpha adrenergic receptor signaling pathway | |||
| Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Reactome | Adrenoceptors | |||
| Adrenaline signalling through Alpha-2 adrenergic receptor | ||||
| Adrenaline,noradrenaline inhibits insulin secretion | ||||
| G alpha (i) signalling events | ||||
| G alpha (z) signalling events | ||||
| Surfactant metabolism | ||||
| WikiPathways | Monoamine GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Platelet Aggregation (Plug Formation) | ||||
| Integration of energy metabolism | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Effect of ring size or an additional heteroatom on the potency and selectivity of bicyclic benzylamine-type inhibitors of phenylethanolamine N-meth... J Med Chem. 1996 Aug 30;39(18):3539-46. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.