Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E2FY
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| Former ID |
DNC011912
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| Drug Name |
1-(2-Isopropoxy-phenyl)-piperazine
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| Synonyms |
1-(2-isopropoxyphenyl)piperazine; 1-(2-Isopropoxy-phenyl)-piperazine; CHEMBL9669; 54013-91-1; 2-isopropoxyphenyl piperazine; SCHEMBL3867980; CTK1F9762; DTXSID40449277; QJULELIONYLITF-UHFFFAOYSA-N; ZINC26001539; BDBM50017448; 1-[2-(methylethoxy)phenyl]piperazine; AKOS010941535; N-[2-(1-methylethoxy)phenyl]piperazine; 1-[2-(1-methylethoxy)phenyl]piperazine; DA-05081; BC4321135; Piperazine, 1-[2-(1-methylethoxy)phenyl]-; FT-0741526
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H20N2O
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| Canonical SMILES |
CC(C)OC1=CC=CC=C1N2CCNCC2
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| InChI |
1S/C13H20N2O/c1-11(2)16-13-6-4-3-5-12(13)15-9-7-14-8-10-15/h3-6,11,14H,7-10H2,1-2H3
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| InChIKey |
QJULELIONYLITF-UHFFFAOYSA-N
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| CAS Number |
CAS 54013-91-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 1A receptor (HTR1A) | Target Info | Inhibitor | [1] |
| 5-HT 1D receptor (HTR1D) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| 5HT1 type receptor mediated signaling pathway | ||||
| Reactome | Serotonin receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy. J Med Chem. 1989 May;32(5):1052-6. | |||
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