Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0EB9M
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| Drug Name |
PMID28627961-Compound-22
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| Drug Type |
Small molecular drug
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| Company |
Glenmark Pharmaceuticals S.A
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| Structure |
 |
Download2D MOL |
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| Formula |
C28H24ClF4N5O2
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| Canonical SMILES |
CC(C)(C)C(=O)NCC1=C(C(=C(C=C1)Cl)C(=O)NC2=CC=CC3=C2N=CN=C3NC4=CC=CC(=C4)C(F)(F)F)F
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| InChI |
1S/C28H24ClF4N5O2/c1-27(2,3)26(40)34-13-15-10-11-19(29)21(22(15)30)25(39)38-20-9-5-8-18-23(20)35-14-36-24(18)37-17-7-4-6-16(12-17)28(31,32)33/h4-12,14H,13H2,1-3H3,(H,34,40)(H,38,39)(H,35,36,37)
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| InChIKey |
NPMRJEGXUPKUTE-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin E synthase (PTGES) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Prostaglandin E synthase (PTGES) | Target's Patent Info | [1] | |
| BioCyc | C20 prostanoid biosynthesis | |||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review.Expert Opin Ther Pat. 2017 Sep;27(9):1047-1059. | |||
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