Drug Information
Drug General Information | Top | |||
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Drug ID |
D0EI5V
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Former ID |
DNC007253
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Drug Name |
Bis-cyclosal-d4TMP
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Synonyms |
bis-cyclosal-d4TMP; CHEMBL376095; 5-methyl-1-[(2R,5S)-5-[[8-[2-[[(2S,5R)-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methoxy]-2-oxo-4H-1,3,2$l^{5}-benzodioxaphosphinin-8-yl]-2-oxo-4H-1,3,2$l^{5}-benzodioxaphosphinin-2-yl]oxymethyl]-2,5-dihydrofuran-2-yl]pyrimidine-2,4-dione; 2,4(1H,3H)-Pyrimidinedione, 1,1'-[(2,2'-dioxido[8,8'-bi-4H-1,3,2-benzodioxaphosphorin]-2,2'-diyl)bis[oxymethylene[(2R,5S)-2,5-dihydro-5,2-furandiyl]]]bis[5-methyl-
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C34H32N4O14P2
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Canonical SMILES |
CC1=CN(C(=O)NC1=O)C2C=CC(O2)COP3(=O)OCC4=C(O3)C(=CC=C4)C5=CC=CC6=C5OP(=O)(OC6)OCC7C=CC(O7)N8C=C(C(=O)NC8=O)C
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InChI |
1S/C34H32N4O14P2/c1-19-13-37(33(41)35-31(19)39)27-11-9-23(49-27)17-47-53(43)45-15-21-5-3-7-25(29(21)51-53)26-8-4-6-22-16-46-54(44,52-30(22)26)48-18-24-10-12-28(50-24)38-14-20(2)32(40)36-34(38)42/h3-14,23-24,27-28H,15-18H2,1-2H3,(H,35,39,41)(H,36,40,42)/t23-,24-,27+,28+,53?,54?/m0/s1
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InChIKey |
KHOMSKKMHVGQFN-QIKIAYFISA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Cholinesterase (BCHE) | Target Info | Inhibitor | [1] |
Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
Nicotinic acetylcholine receptor signaling pathway | ||||
WikiPathways | Irinotecan Pathway |
References | Top | |||
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REF 1 | Bis-cycloSal-d4T-monophosphates: drugs that deliver two molecules of bioactive nucleotides. J Med Chem. 2007 Mar 22;50(6):1335-46. |
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