Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0F5JR
|
|||
| Former ID |
DIB005036
|
|||
| Drug Name |
ONO-1603
|
|||
| Synonyms |
N-(4-Chlorobenzyl)-4-[2(S)-formylpyrrolidin-1-yl]-4-oxobutyramide
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Cognitive impairment [ICD-11: 6D71; ICD-10: F06.7] | Phase 2 | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C16H19ClN2O3
|
|||
| Canonical SMILES |
C1CC(N(C1)C(=O)CCC(=O)NCC2=CC=C(C=C2)Cl)C=O
|
|||
| InChI |
1S/C16H19ClN2O3/c17-13-5-3-12(4-6-13)10-18-15(21)7-8-16(22)19-9-1-2-14(19)11-20/h3-6,11,14H,1-2,7-10H2,(H,18,21)/t14-/m0/s1
|
|||
| InChIKey |
KGDFDVHLEYUZLN-AWEZNQCLSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prolyl endopeptidase (PREP) | Target Info | Modulator | [2] |
| KEGG Pathway | Renin-angiotensin system | |||
| Panther Pathway | Vasopressin synthesis | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002119) | |||
| REF 2 | ONO-1603, a potential antidementia drug, shows neuroprotective effects and increases m3-muscarinic receptor mRNA levels in differentiating rat cerebellar granule neurons. Neurosci Lett. 1996 Aug 23;214(2-3):151-4. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.