Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0G0GZ
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| Former ID |
DNC010552
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| Drug Name |
N-Methyl-1'H-phenothiazine-1'-carboxamide
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| Synonyms |
CHEMBL606338; 52985-78-1; CTK1E4142; DTXSID00601293; BDBM50308426; ZINC13717066; AKOS004108104; N-Methyl-1''H-phenothiazine-1''-carboxamide; 10H-Phenothiazine-10-carboxamide, N-methyl-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H12N2OS
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| Canonical SMILES |
CNC(=O)N1C2=CC=CC=C2SC3=CC=CC=C31
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| InChI |
1S/C14H12N2OS/c1-15-14(17)16-10-6-2-4-8-12(10)18-13-9-5-3-7-11(13)16/h2-9H,1H3,(H,15,17)
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| InChIKey |
VBZPZJCWSNLVCY-UHFFFAOYSA-N
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| CAS Number |
CAS 52985-78-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Acetylcholinesterase (AChE) | Target Info | Inhibitor | [1] |
| Cholinesterase (BCHE) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Glycerophospholipid metabolism | |||
| Cholinergic synapse | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| Pathwhiz Pathway | Phospholipid Biosynthesis | |||
| Pathway Interaction Database | ATF-2 transcription factor network | |||
| WikiPathways | Monoamine Transport | |||
| Biogenic Amine Synthesis | ||||
| Acetylcholine Synthesis | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| Irinotecan Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants. Bioorg Med Chem. 2010 Mar 15;18(6):2232-2244. | |||
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