Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0G3AQ
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| Former ID |
DAP000689
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| Drug Name |
Prazepam
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| Synonyms |
Centrax; Demetrin; Lysanxia; Prazeene; Prazene; Prazepamum; Sedapran; Settima; Trepidan; Verstran; W 4020; Centrac (TN); Centrax (TN); Demetrin (TN); K-373; Lysanxia (TN); Mono Demetrin (TN); Pozapam (TN); Prasepine (TN); Prazene (TN); Prazepamum [INN-Latin]; Reapam (TN); Trepidan (TN); W-4020; Prazepam (JP15/USAN/INN); Prazepam [USAN:INN:BAN:JAN]; 7-Chloro-1-(cyclopropylmethyl)-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one; 7-Chloro-1-(cyclopropylmethyl)-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Chloro-1-cyclopropylmethyl-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one; 7-chloro-1-(cyclopropylmethyl)-5-phenyl-3H-1,4-benzodiazepin-2-one
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| Drug Type |
Small molecular drug
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| Indication | Anxiety disorder [ICD-11: 6B00-6B0Z; ICD-10: R45.0] | Approved | [1], [2] | |
| Therapeutic Class |
Antianxiety Agents
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| Structure |
 |
Download2D MOL |
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| Formula |
C19H17ClN2O
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| Canonical SMILES |
C1CC1CN2C(=O)CN=C(C3=C2C=CC(=C3)Cl)C4=CC=CC=C4
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| InChI |
1S/C19H17ClN2O/c20-15-8-9-17-16(10-15)19(14-4-2-1-3-5-14)21-11-18(23)22(17)12-13-6-7-13/h1-5,8-10,13H,6-7,11-12H2
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| InChIKey |
MWQCHHACWWAQLJ-UHFFFAOYSA-N
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| CAS Number |
CAS 2955-38-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9570, 142196, 4500851, 7847536, 8153008, 10517477, 14874926, 24898436, 29223968, 46505417, 48414363, 48416458, 49857642, 50113069, 57322504, 58107012, 75711993, 103252286, 104307721, 124893449, 125823415, 128658510, 134224569, 134337978, 134982453, 136949643, 137005591, 137440705, 137783726, 144206168, 144207274, 160964826, 162946637, 164788802, 178103849, 179116857, 198988005, 198991803, 223440729, 224927321, 226457573, 250107476, 252356174
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| ChEBI ID |
CHEBI:8362
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| SuperDrug ATC ID |
N05BA11
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| SuperDrug CAS ID |
cas=001088115
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Translocator protein (TSPO) | Target Info | Modulator | [3] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| HTLV-I infection | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7275). | |||
| REF 2 | Drug information of Prazepam, 2008. eduDrugs. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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