Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0G4JI
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| Former ID |
DAP000543
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| Drug Name |
Pyruvic acid
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| Synonyms |
BTS; Brenztraubensaeure; Acetylformic acid; Acide pyruvique; Pyroracemic acid; CH3COCOOH; A-Ketopropionic acid; Alpha-Ketopropionic acid; Alpha-Oxopropionsaeure; Alpha-keto propionic acid; Alpha-ketopropionic acid; P-9250; Pyruvic acid (8CI); Pyruvic acid (natural); Propanoic acid, 2-oxo-(9CI); 2-Ketopropionic acid; 2-Oxopropanoate; 2-Oxopropanoic acid; 2-Oxopropansaeure; 2-Oxopropionic acid; 2-Oxopropionsaeure; 2-oxo(1-14c)propanoic acid; 2-oxo-propionic acid
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| Drug Type |
Small molecular drug
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| Indication | Malnutrition [ICD-11: 5B50-5B71] | Approved | [1], [2] | |
| Therapeutic Class |
Dietary supplement
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| Structure |
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Download2D MOL |
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| Formula |
C3H4O3
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| Canonical SMILES |
CC(=O)C(=O)O
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| InChI |
1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)
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| InChIKey |
LCTONWCANYUPML-UHFFFAOYSA-N
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| CAS Number |
CAS 127-17-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3324, 67115, 583760, 821307, 821314, 822632, 823091, 824014, 827046, 832413, 841522, 3134354, 5571669, 6436244, 7850314, 7890146, 8145308, 8150952, 10506205, 11447561, 11528430, 14716341, 14716592, 15194194, 17435687, 22387984, 22389510, 24439413, 24844228, 24846765, 24898862, 24901426, 24901427, 26702717, 26704720, 26707987, 26709793, 26710008, 26714555, 26714561, 29217748, 36487046, 38372743, 46505692, 46520143, 48414842, 49748488, 53789182, 56373996, 56373999
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| ChEBI ID |
CHEBI:32816
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA transaminase (ABAT) | Target Info | Inhibitor | [3] |
| BioCyc | GABA shunt | |||
| Valine degradation | ||||
| Beta-alanine degradation | ||||
| 4-aminobutyrate degradation | ||||
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Valine, leucine and isoleucine degradation | ||||
| beta-Alanine metabolism | ||||
| Propanoate metabolism | ||||
| Butanoate metabolism | ||||
| Metabolic pathways | ||||
| GABAergic synapse | ||||
| Panther Pathway | Aminobutyrate degradation | |||
| Pyrimidine Metabolism | ||||
| Gamma-aminobutyric acid synthesis | ||||
| Pathwhiz Pathway | Aspartate Metabolism | |||
| Glutamate Metabolism | ||||
| Beta-Alanine Metabolism | ||||
| Valine, Leucine and Isoleucine Degradation | ||||
| Propanoate Metabolism | ||||
| WikiPathways | GABA synthesis, release, reuptake and degradation | |||
| Alanine and aspartate metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4809). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 065200. | |||
| REF 3 | DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. | |||
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