Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0G8DV
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| Former ID |
DIB000109
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| Drug Name |
Ad5CMV-NIS
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| Synonyms |
Sodium iodide symporter adenoviral gene therapy (prostate cancer); Sodium iodide symporter adenoviral gene therapy (prostate cancer), Mayo Clinic
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| Indication | Prostate cancer [ICD-11: 2C82.0; ICD-10: C61; ICD-9: 185] | Phase 1 | [1] | |
| Company |
Mayo Foundation
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium/iodide cotransporter (SLC5A5) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00788307) Gene Therapy and Radioactive Iodine in Treating Patients With Locally Recurrent Prostate Cancer That Did Not Respond to External-Beam Radiation Therapy. U.S. NationalInstitutes of Health. | |||
| REF 2 | Noninvasive Imaging and Radiovirotherapy of Prostate Cancer Using an Oncolytic Measles Virus Expressing the Sodium Iodide Symporter. Mol Ther. 2009 December; 17(12): 2041-2048. | |||
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