Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0G8GA
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| Former ID |
DNC012237
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| Drug Name |
9-Phenyl-9H-purin-6-ylamine
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| Synonyms |
9-phenylpurin-6-amine; CHEMBL62756; 20145-09-9; 9-phenyladenine; 9-Phenyl-9H-purin-6-ylamine; 9H-Purin-6-amine, 9-phenyl-; NSC516599; AC1L6X8K; 6-Amino-9-phenyl-9H-purine; SCHEMBL5146335; CTK1A5420; DTXSID30325733; ZINC1604448; BDBM50009689; AKOS030561953
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H9N5
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| Canonical SMILES |
C1=CC=C(C=C1)N2C=NC3=C(N=CN=C32)N
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| InChI |
1S/C11H9N5/c12-10-9-11(14-6-13-10)16(7-15-9)8-4-2-1-3-5-8/h1-7H,(H2,12,13,14)
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| InChIKey |
QOZYZBRNUYGQNF-UHFFFAOYSA-N
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| CAS Number |
CAS 20145-09-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A1 receptor (ADORA1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| cAMP signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Morphine addiction | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| RANKL Signaling Pathway | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor. J Med Chem. 1991 Sep;34(9):2877-82. | |||
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