Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0H3QX
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| Former ID |
DNC012427
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| Drug Name |
4-Nitro-N-(4-phenyl-thiazol-2-yl)-benzamide
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| Synonyms |
4-Nitro-N-(4-phenyl-thiazol-2-yl)-benzamide; CHEMBL60027; 4-nitro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide; AC1LEVE1; Oprea1_616019; Oprea1_578616; Oprea1_274027; MolPort-001-016-564; ZINC1506439; BDBM50101782; STK401913; AKOS000523323; MCULE-9071819567; BAS 00417263; N-(4-Phenyl-2-thiazolyl)-4-nitrobenzamide; ST50002539; SR-01000394982; SR-01000394982-1
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H11N3O3S
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| Canonical SMILES |
C1=CC=C(C=C1)C2=CSC(=N2)NC(=O)C3=CC=C(C=C3)[N+](=O)[O-]
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| InChI |
1S/C16H11N3O3S/c20-15(12-6-8-13(9-7-12)19(21)22)18-16-17-14(10-23-16)11-4-2-1-3-5-11/h1-10H,(H,17,18,20)
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| InChIKey |
LLSUVHOZHQEGJS-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A1 receptor (ADORA1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| cAMP signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Morphine addiction | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| RANKL Signaling Pathway | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Substituted 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A(1) receptor. Bioorg Med Chem Lett. 2001 Aug 6;11(15):2017-9. | |||
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