Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0H5DU
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| Former ID |
DAP000835
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| Drug Name |
Oxyphencyclimine
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| Synonyms |
Antulcus; Caridan; Daricol; Manir; Naridan; Oxifencicliminum; Oxiphencycliminum; Oxyphencycliminum; Zamanil; Oxifencicliminum [INN-Spanish]; Oxyphencyclimine (INN); Oxyphencyclimine [INN:BAN]; Oxyphencycliminum [INN-Latin]; Benzeneacetic acid, .alpha.-cyclohexyl-.alpha.-hydroxy-, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl ester; (1-methyl-1,4,5,6-tetrahydropyrimidin-2-yl)methyl cyclohexyl(hydroxy)phenylacetate; (1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate; 1,4,5,6-Tetrahydro-1-methyl-2-pyrimidinemethanol-alpha-phenylcyclohexaneglycolate; 1,4,5,6-Tetrahydro-1-methyl-2-pyrimidinylmethyl alpha-cyclohexyl-alpha-phenylglycolat; 1-Methyl-1,4,5,6-tetrahydro-2-pyrimidinylmethyl-alpha-cyclohexylmandelat
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| Drug Type |
Small molecular drug
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| Indication | Peptic ulcer [ICD-11: DA61] | Approved | [1], [2], [3] | |
| Therapeutic Class |
Anticholinergic Agents
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| Company |
Pfizer Laboratories Div Pfizer Inc
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H28N2O3
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| Canonical SMILES |
CN1CCCN=C1COC(=O)C(C2CCCCC2)(C3=CC=CC=C3)O
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| InChI |
1S/C20H28N2O3/c1-22-14-8-13-21-18(22)15-25-19(23)20(24,16-9-4-2-5-10-16)17-11-6-3-7-12-17/h2,4-5,9-10,17,24H,3,6-8,11-15H2,1H3
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| InChIKey |
DUDKAZCAISNGQN-UHFFFAOYSA-N
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| CAS Number |
CAS 125-53-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
10053, 4487440, 7980239, 8152853, 10506089, 11336051, 11361290, 11364500, 11367062, 11369624, 11372991, 11374066, 11377786, 11462262, 11485336, 11489416, 11491621, 11492049, 11495420, 14900524, 29223731, 46507487, 47736543, 47885471, 48334559, 48416369, 50064292, 50300966, 57322371, 85209614, 96025012, 103556001, 103828063, 104307000, 117579805, 124883477, 125823083, 134338115, 134973031, 137009682, 160963730, 178103830, 179038967, 223440573, 226599461, 243595747, 250067444
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| ChEBI ID |
CHEBI:7868
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| SuperDrug ATC ID |
A03AA01
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| SuperDrug CAS ID |
cas=000125531
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| References | Top | |||
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| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7256). | |||
| REF 2 | Drug information of Oxyphencyclimine, 2008. eduDrugs. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 4 | Stereoselective interaction of procyclidine, hexahydro-difenidol, hexbutinol and oxyphencyclimine, and of related antagonists, with four muscarinic receptors. Eur J Pharmacol. 1992 Sep 1;227(1):33-42. | |||
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