Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H6JC
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| Former ID |
DNC011974
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| Drug Name |
1,2-Dihydro-indazol-3-one
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| Synonyms |
1H-Indazol-3-ol; 3-Indazolinone; 7364-25-2; 1H-indazol-3(2H)-one; 100922-96-1; Indazolinone; 3-Hydroxy-1H-indazole; 3-Hydroxyindazole; 1,2-dihydroindazol-3-one; 1,2-Dihydro-3H-indazol-3-one; 3-Oxo-1,2-indazole; 3H-Indazol-3-one, 1,2-dihydro-; 3-Indazolone; 2H-Indazol-3-ol; hydroxyindazole; 2,3-Dihydro-1H-indazol-3-one; NSC 9352; UNII-8E254S9S1R; CCRIS 6800; EINECS 230-904-2; CHEMBL276725; SWEICGMKXPNXNU-UHFFFAOYSA-N; 8E254S9S1R; MFCD00005685; 1H-2-hydroindazol-3-one; benzopyrazolone; 1,2-Dihydro-indazol-3-one; 3-Oxoindazoline
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H6N2O
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=O)NN2
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| InChI |
1S/C7H6N2O/c10-7-5-3-1-2-4-6(5)8-9-7/h1-4H,(H2,8,9,10)
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| InChIKey |
SWEICGMKXPNXNU-UHFFFAOYSA-N
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| CAS Number |
CAS 7364-25-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
| BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Lipoxin biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Vitamin D Receptor Pathway | |||
| Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity. J Med Chem. 1991 Mar;34(3):1028-36. | |||
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