Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H8WV
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| Former ID |
DNC012678
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| Drug Name |
Tyr-D-Ala-Phe-Gly-Tyr-Pro-Thr(Beta-D-Glc)-Gly-NH2
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C49H65N9O16
|
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| Canonical SMILES |
CC(C(C(=O)NCC(=O)N)NC(=O)C1CCCN1C(=O)C(CC2=CC=C(C=C2)O)NC(=O)CNC(=O)C(CC3=CC=CC=C3)NC(=O)C(C)NC(=O)C(CC4=CC=C(C=C4)O)N)OC5C(C(C(C(O5)CO)O)O)O
|
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| InChI |
1S/C49H65N9O16/c1-25(54-44(68)32(50)19-28-10-14-30(60)15-11-28)43(67)56-33(20-27-7-4-3-5-8-27)45(69)53-23-38(63)55-34(21-29-12-16-31(61)17-13-29)48(72)58-18-6-9-35(58)46(70)57-39(47(71)52-22-37(51)62)26(2)73-49-42(66)41(65)40(64)36(24-59)74-49/h3-5,7-8,10-17,25-26,32-36,39-42,49,59-61,64-66H,6,9,18-24,50H2,1-2H3,(H2,51,62)(H,52,71)(H,53,69)(H,54,68)(H,55,63)(H,56,67)(H,57,70)/t25-,26?,32+,33+,34+,35+,36?,39+,40?,41?,42?,49?/m1/s1
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| InChIKey |
ZXTWNLGGKJOAMK-XUDWIOABSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Opioid receptor delta (OPRD1) | Target Info | Inhibitor | [1] |
| Opioid receptor mu (MOP) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Estrogen signaling pathway | ||||
| Morphine addiction | ||||
| cGMP-PKG signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Enkephalin release | ||||
| Opioid proenkephalin pathway | ||||
| Opioid proopiomelanocortin pathway | ||||
| Pathway Interaction Database | IL4-mediated signaling events | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | TCR Signaling Pathway | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Peptide GPCRs | ||||
| Opioid Signalling | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and pharmacological activity of deltorphin and dermorphin-related glycopeptides. J Med Chem. 1997 Aug 29;40(18):2948-52. | |||
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