Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0I1WN
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| Former ID |
DNC009976
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| Drug Name |
1,10-(methylenedi-4,1-phenylene)bismaleimide
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| Synonyms |
Bismaleimide; 13676-54-5; Bismaleimide S; Bis(4-maleimidophenyl)methane; p,p'-Dimaleimidodiphenylmethane; Diphenylmethanebismaleimide; 4,4'-Methylenebis(N-phenylmaleimide); Bis(p-maleimidophenyl)methane; 4,4'-Diphenylmethanedimaleimide; 4,4'-Dimaleimidodiphenylmethane; 4,4'-Diphenylmethanebismaleimide; 4,4'-Biphenylmethanebismaleimide; 4,4'-Bismaleimidodiphenylmethane; 1H-Pyrrole-2,5-dione, 1,1'-(methylenedi-4,1-phenylene)bis-; 4,4'-Methylenebis(phenylmaleimide); p,p'-Methylenebis(N-phenylmaleimide)
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C21H14N2O4
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| Canonical SMILES |
C1=CC(=CC=C1CC2=CC=C(C=C2)N3C(=O)C=CC3=O)N4C(=O)C=CC4=O
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| InChI |
1S/C21H14N2O4/c24-18-9-10-19(25)22(18)16-5-1-14(2-6-16)13-15-3-7-17(8-4-15)23-20(26)11-12-21(23)27/h1-12H,13H2
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| InChIKey |
XQUPVDVFXZDTLT-UHFFFAOYSA-N
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| CAS Number |
CAS 13676-54-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fatty acid amide hydrolase (FAAH) | Target Info | Inhibitor | [1] |
| BioCyc | Anandamide degradation | |||
| KEGG Pathway | Retrograde endocannabinoid signaling | |||
| Panther Pathway | Anandamide degradation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors. J Med Chem. 2009 Dec 10;52(23):7410-20. | |||
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