Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0I4LX
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| Former ID |
DNC007020
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| Drug Name |
AS-1397
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| Synonyms |
AS-1397; 10-(2-(Diethylamino)propionyl)phenothiazine; Methyldifazine; 10-(alpha-Diethylaminopropionyl)-phenothiazine hydrochloride; AC1L1BEE; AC1Q5K0B; Lopac0_000351; SCHEMBL1320997; CHEMBL376514; NIOSH/SO4600000; BDBM13551; CTK5B9958; 2-(diethylamino)-1-(10H-phenothiazin-10-yl)propan-1-one; CCG-204446; LS-105449; 10-(a-diethyl-aminopropionyl)-phenothiazine; SO46000000; Phenothiazine, 10-(2-(diethylamino)propionyl)-; 2-(diethylamino)-1-phenothiazin-10-ylpropan-1-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C19H22N2OS
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| Canonical SMILES |
CCN(CC)C(C)C(=O)N1C2=CC=CC=C2SC3=CC=CC=C31
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| InChI |
1S/C19H22N2OS/c1-4-20(5-2)14(3)19(22)21-15-10-6-8-12-17(15)23-18-13-9-7-11-16(18)21/h6-14H,4-5H2,1-3H3
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| InChIKey |
QCEWCMMSOWEHFC-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cholinesterase (BCHE) | Target Info | Inhibitor | [1] |
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| WikiPathways | Irinotecan Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel heterobivalent tacrine derivatives as cholinesterase inhibitors with notable selectivity toward butyrylcholinesterase. J Med Chem. 2006 Dec 14;49(25):7540-4. | |||
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