Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0I5YK
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| Former ID |
DIB019711
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| Drug Name |
decynium 22
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| Synonyms |
Pseudoisocyanine; 1,1'-Diethyl-2,2'-cyanine; 1-Ethyl-2-((1-ethyl-2(1H)-quinolylidene)methyl)quinolinium; 20766-49-8; CHEMBL1197556; CHEBI:37994; Pseudocyanine; 1-ethyl-2-[(E)-(1-ethylquinolin-2(1H)-ylidene)methyl]quinolinium; Diethylpseudoisocyanine; MLS000532635; AC1NUNMU; AC1Q1IYW; SMR000137574; AC1L2OT9; CBDivE_000769; SCHEMBL737002; 977-96-8 (iodide); 2402-42-8 (chloride); SCHEMBL13619260; 1613-31-6 (bromide); BDBM39687; cid_5717105; CHEBI:38002; DTXSID40174835; MolPort-006-385-585; STK396423; (E)-1,1'-diethyl-2,2'-cyanine; Dy22; 1,1'-diethyl-2,2'-cyanine; NSC-97374
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL
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| Formula |
C23H23IN2
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| Canonical SMILES |
CCN1C(=CC2=[N+](C3=CC=CC=C3C=C2)CC)C=CC4=CC=CC=C41.[I-]
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| InChI |
1S/C23H23N2.HI/c1-3-24-20(15-13-18-9-5-7-11-22(18)24)17-21-16-14-19-10-6-8-12-23(19)25(21)4-2;/h5-17H,3-4H2,1-2H3;1H/q+1;/p-1
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| InChIKey |
GMYRVMSXMHEDTL-UHFFFAOYSA-M
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| CAS Number |
CAS 977-96-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
11129707, 11446526, 11693955, 24434828, 24434860, 43131212, 57364033, 58033102, 74545597, 74545598, 84360938, 85286232, 98997804, 103099763, 104361674, 106138866, 113992713, 117359255, 123085528, 123111311, 124951851, 126676430, 134348510, 135117787, 136368203, 137271740, 137830281, 139572052, 169196638, 171578310, 179205696, 180174208, 223686421, 227023988, 238612847, 246927068, 252620573
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| ChEBI ID |
CHEBI:37993
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Quinone reductase 2 (NQO2) | Target Info | Inhibitor | [2] |
| Solute carrier family 29 member 4 (SLC29A4) | Target Info | Inhibitor | [3] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Podocyte-specific expression of organic cation transporter PMAT: implication in puromycin aminonucleoside nephrotoxicity. Am J Physiol Renal Physiol. 2009 Jun;296(6):F1307-13. | |||
| REF 2 | In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. | |||
| REF 3 | Interaction of organic cations with a newly identified plasma membrane monoamine transporter. Mol Pharmacol. 2005 Nov;68(5):1397-407. | |||
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