Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0I9IX
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| Former ID |
DNC012680
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| Drug Name |
Tyr-D-Ala-Phe-Thr(-D-Glc)-Tyr-Pro-Ser-NH2
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
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| Formula |
C48H64N8O16
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| Canonical SMILES |
CC(C(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)N2CCCC2C(=O)NC(CO)C(=O)N)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(C)NC(=O)C(CC4=CC=C(C=C4)O)N)OC5C(C(C(C(O5)CO)O)O)O
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| InChI |
1S/C48H64N8O16/c1-24(51-43(66)31(49)19-27-10-14-29(59)15-11-27)42(65)52-32(20-26-7-4-3-5-8-26)44(67)55-37(25(2)71-48-40(63)39(62)38(61)36(23-58)72-48)46(69)53-33(21-28-12-16-30(60)17-13-28)47(70)56-18-6-9-35(56)45(68)54-34(22-57)41(50)64/h3-5,7-8,10-17,24-25,31-40,48,57-63H,6,9,18-23,49H2,1-2H3,(H2,50,64)(H,51,66)(H,52,65)(H,53,69)(H,54,68)(H,55,67)/t24-,25-,31+,32+,33+,34+,35+,36-,37+,38-,39+,40-,48+/m1/s1
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| InChIKey |
SAWFTOJFOXCLCQ-MHOYXDTBSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Opioid receptor delta (OPRD1) | Target Info | Inhibitor | [1] |
| Opioid receptor mu (MOP) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| Sphingolipid signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Estrogen signaling pathway | ||||
| Morphine addiction | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Enkephalin release | ||||
| Opioid proenkephalin pathway | ||||
| Opioid proopiomelanocortin pathway | ||||
| Pathway Interaction Database | IL4-mediated signaling events | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| TCR Signaling Pathway | ||||
| Opioid Signalling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and pharmacological activity of deltorphin and dermorphin-related glycopeptides. J Med Chem. 1997 Aug 29;40(18):2948-52. | |||
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