Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0I9RY
|
|||
| Former ID |
DNC011671
|
|||
| Drug Name |
N-Hydroxy-2-methyl-3-naphthalen-2-yl-acrylamide
|
|||
| Synonyms |
CHEMBL367336; N-Hydroxy-2-methyl-3-naphthalen-2-yl-acrylamide; ZINC28109710; BDBM50015187; (E)-2-Methyl-3-(2-naphthalenyl)-2-propenehydroximic acid
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C14H13NO2
|
|||
| Canonical SMILES |
CC(=CC1=CC2=CC=CC=C2C=C1)C(=O)NO
|
|||
| InChI |
1S/C14H13NO2/c1-10(14(16)15-17)8-11-6-7-12-4-2-3-5-13(12)9-11/h2-9,17H,1H3,(H,15,16)/b10-8+
|
|||
| InChIKey |
NPYWWIHEHONKOF-CSKARUKUSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
| BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Lipoxin biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Vitamin D Receptor Pathway | |||
| Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships. J Med Chem. 1990 Mar;33(3):992-8. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.