Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0IW5C
|
|||
| Former ID |
DNC014301
|
|||
| Drug Name |
3,4'-(1H-1,2,4-triazole-3,5-diyl)dipyridine
|
|||
| Synonyms |
CHEMBL1077387; 36770-51-1; 1H-3-(3-pyridyl)-5-(4-pyridyl)-1,2,4-triazole; AC1LJ7ET; SCHEMBL11592234; MolPort-002-889-160; BDBM50311281; STL442012; CCG-42398; ZINC18164784; AKOS002669464; AKOS005228430; AKOS002732698; MCULE-6941572691; FT-0749446; 3,4''-(1H-1,2,4-triazole-3,5-diyl)dipyridine; SR-01000632401-1; 3-(5-pyridin-4-yl-1H-1,2,4-triazol-3-yl)pyridine; 3-(3-Pyridyl)-5-(4-pyridyl)-1H-1,2,4-triazole
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C12H9N5
|
|||
| Canonical SMILES |
C1=CC(=CN=C1)C2=NNC(=N2)C3=CC=NC=C3
|
|||
| InChI |
1S/C12H9N5/c1-2-10(8-14-5-1)12-15-11(16-17-12)9-3-6-13-7-4-9/h1-8H,(H,15,16,17)
|
|||
| InChIKey |
WIHUWTSKKGOEGI-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 36770-51-1
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Xanthine dehydrogenase/oxidase (XDH) | Target Info | Inhibitor | [1] |
| BioCyc | Purine nucleotides degradation | |||
| Urate biosynthesis/inosine 5'-phosphate degradation | ||||
| Guanosine nucleotides degradation | ||||
| Adenosine nucleotides degradation | ||||
| Retinoate biosynthesis II | ||||
| KEGG Pathway | Purine metabolism | |||
| Caffeine metabolism | ||||
| Drug metabolism - other enzymes | ||||
| Metabolic pathways | ||||
| Peroxisome | ||||
| Panther Pathway | Adenine and hypoxanthine salvage pathway | |||
| Purine metabolism | ||||
| Pathwhiz Pathway | Caffeine Metabolism | |||
| Purine Metabolism | ||||
| Reactome | Purine catabolism | |||
| WikiPathways | Oxidative Stress | |||
| Effects of Nitric Oxide | ||||
| Metabolism of nucleotides | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of 3-(2-cyano-4-pyridyl)-5-(4-pyridyl)-1,2,4-triazole, FYX-051 - a xanthine oxidoreductase inhibitor for the treatment of hyperuricemia [... Bioorg Med Chem Lett. 2009 Nov 1;19(21):6225-9. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.