Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0J0BV
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| Former ID |
DIB021030
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| Drug Name |
TCS 5861528
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| Synonyms |
TCS 5861528; 332117-28-9; chembridge-5861528; TCS5861528; CHEMBL1086339; N-(4-butan-2-ylphenyl)-2-(1,3-dimethyl-2,6-dioxopurin-7-yl)acetamide; CheMbridge 5861528; AC1MFLDN; Oprea1_547219; Oprea1_106027; GTPL6276; SCHEMBL10113882; CTK8E7524; DTXSID60386817; MolPort-001-509-243; N-[4-[(2R)-butan-2-yl]phenyl]-2-(1,3-dimethyl-2,6-dioxopurin-7-yl)acetamide; BCP16176; EX-A2273; STK138446; BDBM50318464; AKOS017008161; AKOS000677516; MCULE-9341057356; NCGC00285960-01; NCGC00285960-02; KB-76039; BC600780; BAS 01129942; HY-15065; C-235
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C19H23N5O3
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| Canonical SMILES |
CCC(C)C1=CC=C(C=C1)NC(=O)CN2C=NC3=C2C(=O)N(C(=O)N3C)C
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| InChI |
1S/C19H23N5O3/c1-5-12(2)13-6-8-14(9-7-13)21-15(25)10-24-11-20-17-16(24)18(26)23(4)19(27)22(17)3/h6-9,11-12H,5,10H2,1-4H3,(H,21,25)
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| InChIKey |
ZUTUWJYMCADJHD-UHFFFAOYSA-N
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| CAS Number |
CAS 332117-28-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transformation-sensitive protein p120 (TRPA1) | Target Info | Inhibitor (gating inhibitor) | [2] |
| KEGG Pathway | Inflammatory mediator regulation of TRP channels | |||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6276). | |||
| REF 2 | Attenuation of mechanical hypersensitivity by an antagonist of the TRPA1 ion channel in diabetic animals. Anesthesiology. 2009 Jul;111(1):147-54. | |||
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