Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0JK0I
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| Former ID |
DIB020755
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| Drug Name |
prenalterol
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| Synonyms |
CGP 7760B
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C12H19NO3
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| Canonical SMILES |
CC(C)NCC(COC1=CC=C(C=C1)O)O
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| InChI |
1S/C12H19NO3/c1-9(2)13-7-11(15)8-16-12-5-3-10(14)4-6-12/h3-6,9,11,13-15H,7-8H2,1-2H3/t11-/m0/s1
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| InChIKey |
ADUKCCWBEDSMEB-NSHDSACASA-N
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| CAS Number |
CAS 57526-81-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9736, 7980379, 8177605, 12015540, 15121536, 34707931, 50005694, 50266270, 57312677, 96099954, 103760800, 104339535, 117535178, 127391955, 135260404, 135650853, 137273831, 163693565, 163853022, 164150591, 164232824, 172860850, 179150694, 184547136, 198954444, 223440735, 223533435, 224855346, 225249491, 226599076, 252356181
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| ChEBI ID |
CHEBI:8391
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor beta-3 (ADRB3) | Target Info | Agonist | [2] |
| KEGG Pathway | Calcium signaling pathway | |||
| cGMP-PKG signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Endocytosis | ||||
| Salivary secretion | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Beta3 adrenergic receptor signaling pathway | ||||
| Reactome | Adrenoceptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | Monoamine GPCRs | |||
| Calcium Regulation in the Cardiac Cell | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 537). | |||
| REF 2 | Beta 1- and beta 2-adrenergic receptor-mediated adenylate cyclase stimulation in nonfailing and failing human ventricular myocardium. Mol Pharmacol. 1989 Mar;35(3):295-303. | |||
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