Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0JT3M
|
|||
Former ID |
DNC005277
|
|||
Drug Name |
[2-(3-Benzyl-indol-1-yl)-ethyl]-dimethyl-amine
|
|||
Synonyms |
CHEMBL186621; [2-(3-Benzyl-indol-1-yl)-ethyl]-dimethyl-amine; SCHEMBL3328890
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C19H22N2
|
|||
Canonical SMILES |
CN(C)CCN1C=C(C2=CC=CC=C21)CC3=CC=CC=C3
|
|||
InChI |
1S/C19H22N2/c1-20(2)12-13-21-15-17(14-16-8-4-3-5-9-16)18-10-6-7-11-19(18)21/h3-11,15H,12-14H2,1-2H3
|
|||
InChIKey |
OYHBRXFQPGMFDE-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | 5-HT 6 receptor (HTR6) | Target Info | Inhibitor | [1] |
KEGG Pathway | Calcium signaling pathway | |||
cAMP signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Serotonergic synapse | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
Pathwhiz Pathway | Excitatory Neural Signalling Through 5-HTR 6 and Serotonin | |||
Reactome | Serotonin receptors | |||
G alpha (s) signalling events | ||||
WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
---|---|---|---|---|
REF 1 | Binding of isotryptamines and indenes at h5-HT6 serotonin receptors. Bioorg Med Chem Lett. 2005 Apr 15;15(8):1987-91. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.