Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K3UO
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| Drug Name |
PMID29649907-Compound-39
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| Drug Type |
Small molecular drug
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| Company |
AKARNA THERAPEUTICS, LTD
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| Structure |
 |
Download2D MOL |
||
| Formula |
C28H39N4O5+
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| Canonical SMILES |
CC1=C2C(=NN1)C(=CN(CC2(C)C)C(=O)C3=CC=C(C=C3)OCC[N+]4(CCOCC4)C)C(=O)OC(C)C
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| InChI |
1S/C28H39N4O5/c1-19(2)37-27(34)23-17-31(18-28(4,5)24-20(3)29-30-25(23)24)26(33)21-7-9-22(10-8-21)36-16-13-32(6)11-14-35-15-12-32/h7-10,17,19H,11-16,18H2,1-6H3,(H,29,30)/q+1
|
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| InChIKey |
BFMZLOKFIVIHGO-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Farnesoid X-activated receptor (FXR) | Target Info | Agonist | [1] |
| Target's Patent Info | Farnesoid X-activated receptor (FXR) | Target's Patent Info | [1] | |
| KEGG Pathway | Bile secretion | |||
| Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptor | |||
| Reactome | Recycling of bile acids and salts | |||
| PPARA activates gene expression | ||||
| Endogenous sterols | ||||
| WikiPathways | Nuclear Receptors in Lipid Metabolism and Toxicity | |||
| Nuclear Receptors Meta-Pathway | ||||
| Farnesoid X Receptor Pathway | ||||
| Drug Induction of Bile Acid Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Farnesoid X receptor modulators 2014-present: a patent review.Expert Opin Ther Pat. 2018 May;28(5):351-364. | |||
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