Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K5IP
|
|||
| Drug Name |
Palonosetron + fosnetupitant
|
|||
| Drug Type |
Antibody
|
|||
| Indication | Chemotherapy-induced nausea [ICD-11: MD90; ICD-10: R11; ICD-9: 787] | Approved | [1] | |
| Company |
Helsinn Group
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 3A receptor (HTR3A) | Target Info | Antagonist | [1] |
| Substance-P receptor (TACR1) | Target Info | Antagonist | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Measles | ||||
| Serotonergic synapse | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | CCKR signaling map ST | |||
| 5HT3 type receptor mediated signaling pathway | ||||
| Reactome | G alpha (q) signalling events | |||
| Ligand-gated ion channel transport | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Spinal Cord Injury | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.