Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K8BT
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| Former ID |
DNC008954
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| Drug Name |
Isosorbide-2-(methylcarbamate)-5-benzoate
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| Synonyms |
CHEMBL523500; Isosorbide-2-(methylcarbamate)-5-benzoate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C15H17NO6
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| Canonical SMILES |
CNC(=O)OC1COC2C1OCC2OC(=O)C3=CC=CC=C3
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| InChI |
1S/C15H17NO6/c1-16-15(18)22-11-8-20-12-10(7-19-13(11)12)21-14(17)9-5-3-2-4-6-9/h2-6,10-13H,7-8H2,1H3,(H,16,18)/t10-,11+,12-,13-/m1/s1
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| InChIKey |
XVQSZSYQBPAKTI-YVECIDJPSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Acetylcholinesterase (AChE) | Target Info | Inhibitor | [1] |
| Cholinesterase (BCHE) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Glycerophospholipid metabolism | |||
| Cholinergic synapse | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| Pathwhiz Pathway | Phospholipid Biosynthesis | |||
| Pathway Interaction Database | ATF-2 transcription factor network | |||
| WikiPathways | Irinotecan Pathway | |||
| Monoamine Transport | ||||
| Biogenic Amine Synthesis | ||||
| Acetylcholine Synthesis | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Isosorbide-2-carbamate esters: potent and selective butyrylcholinesterase inhibitors. J Med Chem. 2008 Oct 23;51(20):6400-9. | |||
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