Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0KY1Y
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| Drug Name |
Benzimidazole derivative 16
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| Synonyms |
PMID28627961-Compound-8
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| Drug Type |
Small molecular drug
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| Company |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH PFAU, Roland ARNDT, Kirsten DOODS, Henri HAUEL, Norbert KLINDER, Klaus KUELZER, Raimund MACK, Juergen PRIEPKE, Henning STENKAMP, Dirk
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| Structure |
 |
Download2D MOL |
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| Formula |
C25H30ClFN4O2
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| Canonical SMILES |
CC1=C(C(=C(C=C1)Cl)NC2=NC3=C(N2C)C=C(C(=C3)C(=O)NC4CCC(CC4)(C)C)OC)F
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| InChI |
1S/C25H30ClFN4O2/c1-14-6-7-17(26)22(21(14)27)30-24-29-18-12-16(20(33-5)13-19(18)31(24)4)23(32)28-15-8-10-25(2,3)11-9-15/h6-7,12-13,15H,8-11H2,1-5H3,(H,28,32)(H,29,30)
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| InChIKey |
GHWPMCBIOYWZCT-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin E synthase (PTGES) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Prostaglandin E synthase (PTGES) | Target's Patent Info | [1] | |
| BioCyc | C20 prostanoid biosynthesis | |||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review.Expert Opin Ther Pat. 2017 Sep;27(9):1047-1059. | |||
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