Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0L0MB
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| Former ID |
DAP000844
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| Drug Name |
Acetophenazine
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| Synonyms |
Acephenazinum; Acetophenazina; Acetophenazinum; Tindal; Acetophenazine [INN]; Acetophenazina [INN-Spanish]; Acetophenazinum [INN-Latin]; Ketone, 10-(3-(4-(2-hydroxyethyl-1-piperazinyl)propyl)phenothiazin-2-yl methyl; 1-(10-{3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl}-10H-phenothiazin-2-yl)ethanone; 1-[10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazin-2-yl]ethanone; 10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl methyl ketone; 2-acetyl-10-[3-[4-(b-hydroxyethyl)piperazinyl]propyl]phenothiazine
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| Drug Type |
Small molecular drug
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| Indication | Bipolar disorder [ICD-11: 6A60; ICD-10: F31] | Approved | [1], [2] | |
| Therapeutic Class |
Antipsychotic Agents
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| Structure |
 |
Download2D MOL |
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| Formula |
C23H29N3O2S
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| Canonical SMILES |
CC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN4CCN(CC4)CCO
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| InChI |
1S/C23H29N3O2S/c1-18(28)19-7-8-23-21(17-19)26(20-5-2-3-6-22(20)29-23)10-4-9-24-11-13-25(14-12-24)15-16-27/h2-3,5-8,17,27H,4,9-16H2,1H3
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| InChIKey |
WNTYBHLDCKXEOT-UHFFFAOYSA-N
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| CAS Number |
CAS 2751-68-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9026, 6906047, 7978635, 8145915, 8163237, 14981427, 29285397, 46507036, 48415507, 50064639, 50125831, 57329848, 79129243, 85209527, 103301246, 104343061, 108136254, 117565968, 126671572, 127339546, 127339547, 129608156, 134982102, 135653585, 136350446, 137102211, 142677075, 160964397, 179116543, 184546003, 198962966, 223666661, 226471888, 250102248
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| ChEBI ID |
CHEBI:2401
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| SuperDrug ATC ID |
N05AB07
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| SuperDrug CAS ID |
cas=002751680
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 012254. | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 3 | Atypical antipsychotics: mechanism of action. Can J Psychiatry. 2002 Feb;47(1):27-38. | |||
| REF 4 | Specific therapeutic actions of acetophenazine, perphenazine, and benzquinamide in newly admitted schizophrenic patients. Clin Pharmacol Ther. 1967 Mar-Apr;8(2):249-55. | |||
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