Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0L4TY
|
|||
| Former ID |
DNC007274
|
|||
| Drug Name |
N-(4,6-diphenylpyrimidin-2-yl)-3-methylbutyramide
|
|||
| Synonyms |
CHEMBL376672; 820961-70-4; N-(4,6-diphenylpyrimidin-2-yl)-3-methylbutyramide; SCHEMBL6501467; CTK3E2638; DTXSID50461763; MolPort-007-705-567; HMS3459C01; ZINC13586473; BDBM50157677; AKOS001873749; MCULE-2375799118; N-(4,6-diphenylpyrimidin-2-yl)-3-methylbutanamide; Butanamide, N-(4,6-diphenyl-2-pyrimidinyl)-3-methyl-
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C21H21N3O
|
|||
| Canonical SMILES |
CC(C)CC(=O)NC1=NC(=CC(=N1)C2=CC=CC=C2)C3=CC=CC=C3
|
|||
| InChI |
1S/C21H21N3O/c1-15(2)13-20(25)24-21-22-18(16-9-5-3-6-10-16)14-19(23-21)17-11-7-4-8-12-17/h3-12,14-15H,13H2,1-2H3,(H,22,23,24,25)
|
|||
| InChIKey |
RLCNDGHLHOXEDS-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 820961-70-4
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A1 receptor (ADORA1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| cAMP signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Morphine addiction | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| RANKL Signaling Pathway | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2,4,6-trisubstituted pyrimidines as a new class of selective adenosine A1 receptor antagonists. J Med Chem. 2004 Dec 16;47(26):6529-40. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.