Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0L7RB
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| Former ID |
DNC006145
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| Drug Name |
1-(4-hydroxyphenyl)prop-2-en-1-one
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| Synonyms |
1-(4-hydroxyphenyl)prop-2-en-1-one; 4-acryloylphenol; CHEMBL378577; 95605-38-2; 4-hydroxyphenyl Vinyl Ketone; SCHEMBL2394894; GTPL8841; MolPort-007-991-476; NKPPNPJUBLEKAD-UHFFFAOYSA-N; ZINC28567957; BDBM50177407; AKOS005200150; FCH1599833; 1-(4-Hydroxyphenyl)-2-propene-1-one; EN300-246996
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C9H8O2
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| Canonical SMILES |
C=CC(=O)C1=CC=C(C=C1)O
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| InChI |
1S/C9H8O2/c1-2-9(11)7-3-5-8(10)6-4-7/h2-6,10H,1H2
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| InChIKey |
NKPPNPJUBLEKAD-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA transaminase (ABAT) | Target Info | Inhibitor | [1] |
| Succinate-semialdehyde dehydrogenase (ALDH5A1) | Target Info | Inhibitor | [1] | |
| BioCyc | GABA shunt | |||
| Valine degradation | ||||
| Beta-alanine degradation | ||||
| 4-aminobutyrate degradation | ||||
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Valine, leucine and isoleucine degradation | ||||
| beta-Alanine metabolism | ||||
| Propanoate metabolism | ||||
| Butanoate metabolism | ||||
| Metabolic pathways | ||||
| GABAergic synapse | ||||
| Panther Pathway | Aminobutyrate degradation | |||
| Pyrimidine Metabolism | ||||
| Gamma-aminobutyric acid synthesis | ||||
| Pathwhiz Pathway | Aspartate Metabolism | |||
| Glutamate Metabolism | ||||
| Beta-Alanine Metabolism | ||||
| Valine, Leucine and Isoleucine Degradation | ||||
| Propanoate Metabolism | ||||
| WikiPathways | GABA synthesis, release, reuptake and degradation | |||
| Alanine and aspartate metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. Bioorg Med Chem Lett. 2006 Feb;16(3):592-5. | |||
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