Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0LL4C
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| Former ID |
DNC001448
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| Drug Name |
TIP
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| Synonyms |
oxide; 16833-27-5; Oxide anion; Oxide ion; Atomic oxygen(2-); Oxygen, ion(O2-); oxide(2-); AC1L4Q4G; AC1Q22UN; CTK4D2966; CHEBI:29356; O(2-)
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
O-2
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| Canonical SMILES |
[O-2]
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| InChI |
1S/O/q-2
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| InChIKey |
AHKZTVQIVOEVFO-UHFFFAOYSA-N
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| CAS Number |
CAS 16833-27-5
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:29356
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Opioid receptor delta (OPRD1) | Target Info | Antagonist | [1] |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| Sphingolipid signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Enkephalin release | ||||
| Opioid proenkephalin pathway | ||||
| Opioid proopiomelanocortin pathway | ||||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The TIPP opioid peptide family: development of delta antagonists, delta agonists, and mixed mu agonist/delta antagonists. Biopolymers. 1999;51(6):411-25. | |||
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