Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0M1ND
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| Drug Name |
Pyrimidinyl ethylenediamine derivative 1
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| Synonyms |
PMID26413912-Compound-79
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| Drug Type |
Small molecular drug
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| Company |
JANSSEN PHARMACEUTICA NV HAWRYLUK, Natalie, A. BREITENBUCHER, J., Guy JONES, William, M. CHAMBERS, Alison, L. KEITH, John, M. SEIERSTAD, Mark
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| Structure |
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Download2D MOL |
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| Formula |
C19H14ClF5N4
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| Canonical SMILES |
C1=CC(=C(C=C1C2=CC(=NC=N2)NCC(C3=CC(=C(C=C3)F)F)N)Cl)C(F)(F)F
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| InChI |
1S/C19H14ClF5N4/c20-13-5-11(1-3-12(13)19(23,24)25)17-7-18(29-9-28-17)27-8-16(26)10-2-4-14(21)15(22)6-10/h1-7,9,16H,8,26H2,(H,27,28,29)/t16-/m0/s1
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| InChIKey |
WKWUCPXAFUCNHR-INIZCTEOSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fatty acid amide hydrolase (FAAH) | Target Info | Inhibitor | [1] |
| Fatty-acid amide hydrolase 1 (FAAH1) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | Fatty acid amide hydrolase (FAAH) | Target's Patent Info | [1] | |
| Fatty-acid amide hydrolase 1 (FAAH1) | Target's Patent Info | [1] | ||
| BioCyc | Anandamide degradation | |||
| KEGG Pathway | Retrograde endocannabinoid signaling | |||
| Panther Pathway | Anandamide degradation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Fatty acid amide hydrolase inhibitors: a patent review (2009-2014).Expert Opin Ther Pat. 2015;25(11):1247-66. | |||
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