Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0M3RI
|
|||
| Drug Name |
CART-138 cells
|
|||
| Drug Type |
CAR T Cell Therapy
|
|||
| Indication | Multiple myeloma [ICD-11: 2A83; ICD-10: C90.0] | Phase 1/2 | [1] | |
| Company |
Chinese PLA General Hospital
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Syndecan-1 (SDC1) | Target Info | CAR-T-Cell-Therapy | [1] |
| Pathway Interaction Database | Beta3 integrin cell surface interactions | |||
| Integrins in angiogenesis | ||||
| Proteoglycan syndecan-mediated signaling events | ||||
| Syndecan-1-mediated signaling events | ||||
| Beta5 beta6 beta7 and beta8 integrin cell surface interactions | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01886976) Treatment of Chemotherapy Refractory Multiple Myeloma by CART-138 | |||
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