Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0M9OF
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| Former ID |
DNC003603
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| Drug Name |
3-(1H-Indol-2-yl)-1H-quinolin-2-one
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| Synonyms |
3-(1H-indol-2-yl)quinolin-2(1H)-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H12N2O
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| Canonical SMILES |
C1=CC=C2C(=C1)C=C(C(=O)N2)C3=CC4=CC=CC=C4N3
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| InChI |
1S/C17H12N2O/c20-17-13(9-11-5-1-4-8-15(11)19-17)16-10-12-6-2-3-7-14(12)18-16/h1-10,18H,(H,19,20)
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| InChIKey |
OSFGHYZLBDAJTP-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Optimization of the indolyl quinolinone class of KDR (VEGFR-2) kinase inhibitors: effects of 5-amido- and 5-sulphonamido-indolyl groups on pharmaco... Bioorg Med Chem Lett. 2004 Jan 19;14(2):351-5. | |||
| REF 2 | Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitors. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5907-12. | |||
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