Drug Information
Drug General Information | Top | |||
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Drug ID |
D0N8AO
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Former ID |
DNC006783
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Drug Name |
4-(4-benzenesulfonamidophenyl)piperazine
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Synonyms |
4-(4-benzenesulfonamidophenyl)piperazine; CHEMBL426332; SCHEMBL18553766
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H19N3O2S
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Canonical SMILES |
C1CN(CCN1)C2=CC=C(C=C2)NS(=O)(=O)C3=CC=CC=C3
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InChI |
1S/C16H19N3O2S/c20-22(21,16-4-2-1-3-5-16)18-14-6-8-15(9-7-14)19-12-10-17-11-13-19/h1-9,17-18H,10-13H2
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InChIKey |
LHOHHFFMBNKDDU-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 6 receptor (HTR6) | Target Info | Inhibitor | [1] |
KEGG Pathway | Calcium signaling pathway | |||
cAMP signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Serotonergic synapse | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
Pathwhiz Pathway | Excitatory Neural Signalling Through 5-HTR 6 and Serotonin | |||
Reactome | Serotonin receptors | |||
G alpha (s) signalling events | ||||
WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors. J Med Chem. 2006 Aug 24;49(17):5217-25. |
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