Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0NJ3Q
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| Former ID |
DIB005199
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| Drug Name |
WZ-3146
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| Synonyms |
WZ-4002; WZ-8040; EGFR-T790M kinase inhibitors (lung cancer); EGFR-T790M kinase inhibitors (lung cancer), Gatekeeper Pharmaceuticals
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| Drug Type |
Small molecular drug
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| Indication | Lung cancer [ICD-11: 2C25.0; ICD-9: 162] | Investigative | [1] | |
| Company |
Gatekeeper Pharmaceuticals Inc
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| Structure |
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Download2D MOL |
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| Formula |
C24H25ClN6O2
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| Canonical SMILES |
CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC(=C4)NC(=O)C=C)Cl
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| InChI |
1S/C24H25ClN6O2/c1-3-22(32)27-18-5-4-6-20(15-18)33-23-21(25)16-26-24(29-23)28-17-7-9-19(10-8-17)31-13-11-30(2)12-14-31/h3-10,15-16H,1,11-14H2,2H3,(H,27,32)(H,26,28,29)
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| InChIKey |
APHGZZPEOCCYNO-UHFFFAOYSA-N
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| CAS Number |
CAS 1214265-56-1
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:94728
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1797). | |||
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