Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0NS1X
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| Former ID |
DIB002732
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| Drug Name |
SAR-650984
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| Synonyms |
Anti-CD38 monoclonal antibody (leukemia), ImmunoGen/sanofi-aventis
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| Drug Type |
Antibody
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| Indication | Haematological malignancy [ICD-11: 2B33.Y] | Phase 1/2 | [1] | |
| Company |
ImmunoGen Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cyclic ADP-ribose hydrolase 1 (CD38) | Target Info | . | [2] |
| KEGG Pathway | Nicotinate and nicotinamide metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Hematopoietic cell lineage | ||||
| Oxytocin signaling pathway | ||||
| Salivary secretion | ||||
| Pancreatic secretion | ||||
| Epstein-Barr virus infection | ||||
| NetPath Pathway | Leptin Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| Panther Pathway | CCKR signaling map ST | |||
| WikiPathways | Oxytocin signaling | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01084252) Phase 1/2 Dose Escalation and Efficacy Study of Anti-CD38 Monoclonal Antibody in Patients With Selected CD38+ Hematological Malignancies. U.S. National Institutes of Health. | |||
| REF 2 | Clinical pipeline report, company report or official report of Sanofi-Aventis. | |||
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