Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0O7SM
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| Former ID |
DNC013990
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| Drug Name |
BUDDLEDIN A
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| Synonyms |
BUDDLEDIN A; CHEBI:3206; CHEMBL485981; AC1NQYK4; 62346-20-7; CHEBI:542717; BDBM50241571; C09623; [(1S,5E,8R,9R)-6,10,10-trimethyl-2-methylidene-7-oxo-8-bicyclo[7.2.0]undec-5-enyl] acetate; [(1S,5E,8R,9R)-6,10,10-trimethyl-2-methylene-7-oxo-8-bicyclo[7.2.0]undec-5-enyl] acetate; (1R,2R,4E,9S)-4,11,11-trimethyl-8-methylidene-3-oxobicyclo[7.2.0]undec-4-en-2-yl acetate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C17H24O3
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| Canonical SMILES |
CC1=CCCC(=C)C2CC(C2C(C1=O)OC(=O)C)(C)C
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| InChI |
1S/C17H24O3/c1-10-7-6-8-11(2)15(19)16(20-12(3)18)14-13(10)9-17(14,4)5/h8,13-14,16H,1,6-7,9H2,2-5H3/b11-8+/t13-,14+,16-/m1/s1
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| InChIKey |
SXWKLEULMBLXJM-PCRFWOPQSA-N
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| CAS Number |
CAS 62346-20-7
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:3206
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
| BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Lipoxin biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Vitamin D Receptor Pathway | |||
| Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel and known constituents from Buddleja species and their activity against leukocyte eicosanoid generation. J Nat Prod. 1999 Sep;62(9):1241-5. | |||
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