Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0P1FJ
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| Former ID |
DNC000245
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| Drug Name |
Aprophen
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| Synonyms |
Aprofene; Aprophen; Aprofen; Aprophenum; Aprofene [INN]; 3563-01-7; 2-Diethylaminoethyl 2,2-diphenylpropionate; Aprofenum [INN-Latin]; Aprofeno [INN-Spanish]; UNII-PL791XXJ7B; PL791XXJ7B; CHEMBL26505; 2-(Diethylamino)ethyl 2,2-diphenylpropanoate; 2,2-Diphenylpropionic acid 2-diethylaminoethyl ester; BRN 2509326; NCGC00160676-01; Propionic acid, 2,2-diphenyl-, 2-(diethylamino)ethyl ester; DSSTox_CID_26294; DSSTox_RID_81519; DSSTox_GSID_46294; alpha,alpha-Diphenylpropionic acid beta-diethylaminoethyl ester
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C21H27NO2
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| Canonical SMILES |
CCN(CC)CCOC(=O)C(C)(C1=CC=CC=C1)C2=CC=CC=C2
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| InChI |
1S/C21H27NO2/c1-4-22(5-2)16-17-24-20(23)21(3,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15H,4-5,16-17H2,1-3H3
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| InChIKey |
DIDYGLSKVUKRRP-UHFFFAOYSA-N
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| CAS Number |
CAS 3563-01-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
6310258, 8194443, 14951174, 29216370, 43127515, 50025618, 57318020, 57825662, 79687531, 81093318, 85209440, 88826488, 103193266, 103919137, 104349726, 108205614, 126424253, 127738368, 134222727, 134339721, 135026637, 144205532, 164235787, 165805006, 170466081, 179294171, 198989935, 228472588, 249950688
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | The muscarinic antagonists aprophen and benactyzine are noncompetitive inhibitors of the nicotinic acetylcholine receptor. Mol Pharmacol. 1987 Nov;32(5):678-85. | |||
| REF 2 | M1 muscarinic antagonists interact with sigma recognition sites. Life Sci. 1991;49(17):1229-35. | |||
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