Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0P3JU
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| Former ID |
DAP000240
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| Drug Name |
Clorazepate
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| Synonyms |
Chlorazepate; Tranxene; Cchlorazepic acid; Chlorazepic acid; Clorazepate dipotassium; Clorazepic acid; Clorazepic acid [BAN]; Gen-xene; Novo-Clopate; Tranxene (Cherazepate dipotasium); Tranxene (TN); Novo-Clopate (TN); (Chloromethyl)(dimethyl)(tridecyloxy)silane; 7-Chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid; 7-chloro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylic acid; 7-chloro-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Anxiety disorder [ICD-11: 6B00-6B0Z] | Approved | [1], [2] | |
| Therapeutic Class |
Hypnotics and Sedatives
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| Company |
Taro Pharmaceutical Industries Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C16H11ClN2O3
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| Canonical SMILES |
C1=CC=C(C=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)C(=O)O
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| InChI |
1S/C16H11ClN2O3/c17-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)19-14(16(21)22)15(20)18-12/h1-8,14H,(H,18,20)(H,21,22)
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| InChIKey |
XDDJGVMJFWAHJX-UHFFFAOYSA-N
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| CAS Number |
CAS 23887-31-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9138, 4821016, 7849641, 7978977, 8151816, 10542638, 14950450, 29221964, 46506595, 50066179, 50071296, 74906350, 96079582, 103807498, 104239421, 104301676, 117469038, 129671809, 134337554, 134994500, 137089233, 137240524, 160963973, 162311076, 163299016, 179225622, 198993218, 223365884, 224779999, 227838419, 241037568, 250143278
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| ChEBI ID |
CHEBI:3761
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| ADReCS Drug ID | BADD_D00506 ; BADD_D00507 | |||
| SuperDrug ATC ID |
N05BA05
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Translocator protein (TSPO) | Target Info | Modulator | [3] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| HTLV-I infection | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7548). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 071852. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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