Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0P4PQ
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| Former ID |
DNC003078
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| Drug Name |
Lanosterol
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| Synonyms |
lanosterol; 79-63-0; Lanosterin; Lanster; Botalan base 138; Lanosta-8,24-dienol; Lanosta-8,24-dien-3beta-ol; (3beta)-lanosta-8,24-dien-3-ol; UNII-1J05Z83K3M; NSC60677; Botalan base; CHEBI:16521; Lanosta-8,24-dien-3.beta.-ol; CAHGCLMLTWQZNJ-BQNIITSRSA-N; 1J05Z83K3M; MFCD00021108; Lanostadien-3-beta-ol; NSC 60677; Lanosta-8,24-dien-3-ol, (3beta)-; Lanosta-8,24-dien-3-ol; Lanosta-8,24-dien-3-ol, (3.beta.)-; Lanosta-8,24-dien-3-beta-ol; 4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol; EINECS 201-214-9
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C30H50O
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| Canonical SMILES |
CC(CCC=C(C)C)C1CCC2(C1(CCC3=C2CCC4C3(CCC(C4(C)C)O)C)C)C
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| InChI |
1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1
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| InChIKey |
CAHGCLMLTWQZNJ-BQNIITSRSA-N
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| CAS Number |
CAS 79-63-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
2905, 4861, 108662, 4266378, 7888607, 8138329, 8143526, 9395181, 12158930, 15302777, 24896283, 24896417, 25651433, 26757817, 30045540, 57309786, 57400449, 79349088, 87565551, 87623957, 92298600, 103514947, 104491139, 126523909, 127287164, 127287165, 127287166, 134368260, 135651499, 137237308, 140346043, 162094640, 163667483, 164811548, 166211000, 179293068, 198956768, 226512170, 241225868, 249929901, 252402925, 252450022
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| ChEBI ID |
CHEBI:16521
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Lanosterol synthase (LSS) | Target Info | Inhibitor | [2] |
| BioCyc | Cholesterol biosynthesis II (via 24,25-dihydrolanosterol) | |||
| Cholesterol biosynthesis III (via desmosterol) | ||||
| Cholesterol biosynthesis I | ||||
| Superpathway of cholesterol biosynthesis | ||||
| Lanosterol biosynthesis | ||||
| KEGG Pathway | Steroid biosynthesis | |||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| Panther Pathway | Cholesterol biosynthesis | |||
| Pathwhiz Pathway | Steroid Biosynthesis | |||
| Reactome | Cholesterol biosynthesis | |||
| Activation of gene expression by SREBF (SREBP) | ||||
| WikiPathways | Activation of Gene Expression by SREBP (SREBF) | |||
| SREBP signalling | ||||
| Cholesterol Biosynthesis | ||||
| Cholesterol biosynthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2746). | |||
| REF 2 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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