Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0P5OF
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| Former ID |
DNC012430
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| Drug Name |
7-Methoxy-1H-indazole
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| Synonyms |
7-methoxy-1H-indazole; 133841-05-1; 1H-Indazole, 7-methoxy-; CHEMBL15921; ACMC-20aa2r; 7-METHOXYINDAZOLE; SCHEMBL5483794; SCHEMBL18003573; CTK0H0012; KS-00000DHI; DTXSID90439880; QCBANHQTMCETBI-UHFFFAOYSA-N; MolPort-009-199-308; BDBM50099399; ANW-63985; ZINC26894532; AKOS024124789; AKOS006290288; TRA0059918; AS-8550; RP01575; PB32675; RTC-062053; AN-6943; KB-46446; AC-29510; SY032798; SC-54780; AK-58155; AJ-82859; 1429222-35-4; TC-062053; DB-062996; Y7436; ST24045679; FT-0767863; 4CH-023995; CS-0043993; AM20020408; MFCD08752584 (97%); Q-2252
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C8H8N2O
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| Canonical SMILES |
COC1=CC=CC2=C1NN=C2
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| InChI |
1S/C8H8N2O/c1-11-7-4-2-3-6-5-9-10-8(6)7/h2-5H,1H3,(H,9,10)
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| InChIKey |
QCBANHQTMCETBI-UHFFFAOYSA-N
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| CAS Number |
CAS 133841-05-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nitric-oxide synthase brain (NOS1) | Target Info | Inhibitor | [1] |
| BioCyc | Citrulline-nitric oxide cycle | |||
| KEGG Pathway | Arginine and proline metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Phagosome | ||||
| Circadian entrainment | ||||
| Long-term depression | ||||
| Salivary secretion | ||||
| Alzheimer's disease | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Panther Pathway | CCKR signaling map ST | |||
| Pathwhiz Pathway | Arginine and Proline Metabolism | |||
| Reactome | ROS production in response to bacteria | |||
| Nitric oxide stimulates guanylate cyclase | ||||
| WikiPathways | Monoamine Transport | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
| Spinal Cord Injury | ||||
| Alzheimers Disease | ||||
| Effects of Nitric Oxide | ||||
| Serotonin Transporter Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Inhibition of neuronal nitric oxide synthase by 7-methoxyindazole and related substituted indazoles. Bioorg Med Chem Lett. 2001 May 7;11(9):1153-6. | |||
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