Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0PU1J
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| Former ID |
DNC000365
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| Drug Name |
BW B218C
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| Synonyms |
BW B218C; BW-B218C; ZLIVOFMPDUIULQ-VAWYXSNFSA-N; 134470-36-3; AC1O5RJN; SCHEMBL6008832; N-(1-Methyl-3-(3-phenoxyphenyl)prop-2-enyl)acetohydroxamic acid; N-hydroxy-N-[(E)-4-(3-phenoxyphenyl)but-3-en-2-yl]acetamide; Acetamide, N-hydroxy-N-(1-methyl-3-(3-phenoxyphenyl)-2-propenyl)-; (+)-(E)-N-[1-methyl-3-(3-phenoxyphenyl)prop-2-enyl]acetohydroxamic acid; N-[(E)-3-(3-Phenoxyphenyl)-1-methyl-2-propenyl]acetohydroxamic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H19NO3
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| Canonical SMILES |
CC(C=CC1=CC(=CC=C1)OC2=CC=CC=C2)N(C(=O)C)O
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| InChI |
1S/C18H19NO3/c1-14(19(21)15(2)20)11-12-16-7-6-10-18(13-16)22-17-8-4-3-5-9-17/h3-14,21H,1-2H3/b12-11+
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| InChIKey |
ZLIVOFMPDUIULQ-VAWYXSNFSA-N
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| CAS Number |
CAS 134470-36-3
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
| BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Lipoxin biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Vitamin D Receptor Pathway | |||
| Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Hydroxamic acids and hydroxyureas as novel, selective 5-lipoxygenase inhibitors for possible use in asthma. Agents Actions Suppl. 1991;34:189-99. | |||
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